Day and night changes in energy expenditure of patients on automated peritoneal dialysis

Rationale Automated peritoneal dialysis (APD) treatment for end-stage kidney disease affords patients a degree of autonomy in everyday life. Clinical investigations their energy expenditure (EE) are usually based on resting EE, which could mask day and night variations EE. The aim this study, therefore, was to compare the components EE APD healthy control (C) subjects. Material method Patients treated with more than 3 months were compared C volunteers matched age lean body mass (LBM). Biochemical analyses performed composition determined by DEXA adjust LBM. Total its different respiratory quotients (RQ) measured gas exchange calorimetric chambers. Spontaneous total activity-related (AEE) also free-living conditions over 4 days calibrated accelerometer heart rate monitor. Results (n = 7) did not differ composition. REE between two groups. However, prandial increase adjusted dietary intake higher (+57.5 ± 12.71 kcal/h) subjects (+33.8 10.5 kcal/h, p 0.003) nocturnal decrease tended be lower undergoing sessions (- 4.53 8.37 11.8 7.69 0.059). Resting RQ (0.91 0.09 vs 0.81 0.04, 0.032) significantly patients, indicating preferential use glucose substrate potentially absorbed across peritoneum. AEE (595.9 383.2 kcal/d) (1205.2 370.5 kcal/d, 0.011). In contrast, intakes (1986 465 2083 377 0.677). Conclusion Although groups had identical